Heartworm Disease and Arizona Gundogs 

Heartworm disease (HWD) is caused by infection with the nematode (roundworm) known scientifically as Dirofilaria immitis.  Dogs become infected after being bitten by an infected mosquito.  About half of the mosquito species in the US can carry heartworm larvae, but only a few have been proven to play a significant role in transmitting HWD.  Heartworm larvae mature to their third stage within the mosquito before being injected into a dog during a blood meal.  The third stage larvae migrate to the connective tissues under the skin, where they molt into fourth stage larvae within three days of the bite.  The larvae then remain in the connective tissues for two or three months before molting into young adults (fifth stage), migrating to the arteries of the lungs and adjacent right side of the heart, and maturing to begin producing offspring (microfilariae) six to nine months after infection.  These microfilariae, in turn, are taken in by feeding mosquitoes, where the cycle begins again.  

Dogs with heartworm infection are frequently asymptomatic (show no signs), particularly when worm burdens are low.  Common symptoms of HWD in dogs include cough, lethargy, and exercise intolerance (tire rapidly).   Prolonged or severe infections may also result in weight loss, fainting or collapse (syncope), and accumulation of fluid within the abdomen (ascites) resulting in a bloated appearance.  The worst cases may result in respiratory difficulty, formation of blood clots in the lungs, liver enlargement, heart failure, and death. 

Any dog that is not taking heartworm preventative in an area where heartworm is found is susceptible to infection.  While infection can occur at any age, most dogs are between 3 and 8 years old at the time of diagnosis.  Gundogs and working hounds are likely to be at increased risk due to the fact that many spend a good portion of their time outdoors when mosquitoes are most active.  Wild canines, domestic (and presumably wild) cats, and ferrets may be infected with heartworm disease in the same manner as dogs.  Humans are a “dead end” host for heartworms; while they can be infected “accidentally,” people do not become visibly ill or serve as reservoirs for disease.  

There are areas where heartworms are endemic (present at all times) throughout the country.  While Arizona is generally considered to have low prevalence of HWD, there are several “pockets” of endemism in the Valley of the Sun, most of which are in or near agricultural (or formerly agricultural) areas using canals and flood irrigation on the urban fringe.  The risk in Arizona increases every year, however, as more and more people—nearly 1000 per month in both Gilbert and Chandler—move from California and the East Coast, where nearly 100% of unprotected dogs can be expected to contract HWD eventually.  Add this reservoir of infected dogs to the mosquito hatcheries (that developers call water features) built into most subdivisions these days, and it’s easy to see why the risk to dogs in Arizona is growing.  The best way to find out about relative risks in your area is to speak with a veterinarian in the neighborhood and find out how many cases they diagnose—more than a few cases per YEAR suggests that there may be increased risk in your area. 

We are fortunate to have safe and effective preventatives for HWD, which may be given on daily, monthly, or six-month intervals (depending upon the medication).  By and large, these preventatives are inexpensive, safe, and very effective.  Many of these medications also control at least a portion of the intestinal parasites common to dogs (either on their own or as a result of additional parasiticides).  Most dogs should be tested for heartworm infection prior to beginning any preventative.  The American Heartworm Association also recommends annual testing for dogs on preventative to detect infections that can occur as a result of treatment lapses or failures. 

Unprevented heartworm infections can be life-threatening, resulting in inflammation in the lungs, liver congestion, and heart or kidney failure.  Established infections are typically treated with compounds related to arsenic.  In addition to being expensive, treatment often carries considerable risk and the need for several weeks’ rest.  Mild to moderate infections carry a good prognosis when treated appropriately, but complications are relatively common in more-severely infected patients.  Re-infection can occur if a treated dog is not taking appropriate preventatives.  

For these reasons, I typically recommend that my patients be on year-round heartworm preventative.  While using preventatives from May through December may effectively prevent infection in Arizona , it’s difficult to form a habit (in this case giving preventative monthly) six months at a time and monthly doses are more likely to be missed if the drug is given only six of every twelve months.  Constant protection is particularly important for dogs that travel to endemic areas (for trialing, shows, etc.) and those that spend most of their time outdoors (yard and kennel dogs).    

BG 

Billy Griswold

billygdvm@hotmail.com

1565 E Kent Ave.

Chandler, AZ 85225-1643

(480) 782-9522 (phone/fax)

(480) 734-5959 (mobile)